In my limited experience, I have to go with the PX4 full size for all around best and the M&P Shield for it's ease of concealment. The PX4 is easily the nicest shooting gun I've ever felt. Accurate right out of the box, minimal felt recoil and darned nice looking, to boot. But, that being said, I have to agree with a number of the previous posters that what I may think is the best for me, may not be the best for everyone...Pick the one that works for you, grip, caliber, size and primary use and you'll never be sorry.
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