Having owned and carried both I have no preference in a quality handgun. I enjoy my 1911s and Glock pistols as much as I enjoy my Ruger SP101 and GP100 and as I do my Ruger SA revolvers. When I was an LEO, I carried a Colt Series 80 Government Model, A SIG P220, a Beretta 92, and a Smith & Wesson 686 (at different times, of course) and I was comfortable shooting any of them.
The dynamics of each type of handgun are, of course, different. Both types of handguns have their advantages and disadvantages, with the most predominant difference being in capacity and manual of arms. With either, bullet placement and control is tantamount regardless of the type or capacity. Personally, I would rather hit with 5 or six than miss with 10+.
Personally, I have found revolvers and semi-automatic pistols that I cannot shoot well due to a myriad of factors and they no longer have a place in my hand.
When I am in the woods, I favor the revolver of sufficient caliber and adequate means of quick re-loading. When I'm on the street among the populace, I prefer a pistol of sufficient caliber and capacity and, as with the revolver, an adequate means of quick re-loading.
The Ruger SP101, at its widest point, measures 1.349". The Glock G19, in comparison, measures 1.18". Not enough difference to concern ones self about. The 15+1/17+1/19+1/33+1 magazine capacity; however, gives the Glock G19 a distinct advantage over the Ruger SP101's 5+0 capacity (in .38 special/.357 magnum configuration).
Someone who by preference uses a weapon holding only six rounds may be perceived as being confident in his skills ("Beware the man with one gun"), when more modern designs holding several times that much ammunition are readily available. With that said, my EDC is either a Glock G36 (7+1 with magazine extension), a Bersa 45UC (7+1), or a Ruger SP101 (5+0), all with adequate reloads, and I'm at home with any of them.
Of all this, I favor the SA Ruger Blackhawk revolver chambered in .38 special/.357 magnum. As I said previously, it is carried in the woods and not on the street.