Overkill, of course, but my favorite deer rifle is a Parker Hale surplus conversion German mauser in .308 Norma Magnum. I prefer it because it is so accurate and I have learned all of its range variations. I live in NY state and have shot a deer here at further than 40 yards only once. When I was stationed in Texas I did shoot a deer at 425 to 450 yards with the rifle. (I don't advocate doing that unless you have practiced with your rifle and understand the ballistics.) All but one deer was one shot. Most dropped in their tracks.
I have also used 30-30, 30-06, 35Rem, 12 ga, and 45-70.
I'm too old to stomp around the woods now, but I love my memories