9MM version may be better suited for Ma...
I carry the PT-145 & love it!
For a woman, I'd recommend the 9MM version (PT-247 or PT-111). I say that because I've let several women in my classes shoot my PT-145, and most of them were intimidated by the heavy recoil. When they shot my PT-111, it was much more comfortable and easier for them to control. For defense, add good quality ammo with proven stopping power.
I know that at least two women who have had a chance to try various guns, bought the 9MM as their carry piece.
I found very early that when shooting either gun, it's important to lock your wrists to prevent stovepipes.