Thank you Cyr for your well thought comments on this subject. I have a slightly different take on the subject.
I am assuming the OP wants a quick access option for a gun in case something wakes him up in the middle of the night or during the day time if he is a third shifter. I am of the school of thought that the best safe in this case is a safe room. My bedroom has a reinforced door equipped with a solid deadbolt lock. Near my bed is a chair with a robe, set of slippers, and my Glock G22 in a Galco Miami Classic shoulder holster with two spare magazines. If something wakes me up in the middle of the night I have my Glock with spare ammo, presentable attire, and "tactical" foot ware on my person before I even leave the bedroom. I am not saying this is the best option for everyone, or even anyone other than myself, but it works for me. If you can learn from my experience, so much the better.