Go here.
Link Removed
It lists bullet weights from 160gr to 300gr on the standard pressure .45 Colt page with about a dozen different powders. There's a separate page for the hot rod "Ruger Only" hunting stuff. Just keep those out of Colts or Colt clones because they are NOT designed to shoot that high a pressure load in the .45 Colt.
FYI-- If you have a new model Vaquero (it's built on a slightly smaller frame than the original), it's NOT rated for the hot 'Ruger Only' loads.
Personally, I keep with 230gr or higher bullet weights with a mid range or higher powder charge just to keep the powder residue down (800-850fps or there abouts). The .45 Colt case is a BIG pistol case and the walls are thicker than you think. If you go to a light bullet or a low powder charge, you end up with sooted up cases because the brass doesn't expand fully and the gasses blow back in the chamber. Getting rid of all of it is real hard but you can get it down to a little residue around the case mouth pretty easily. Blowback isn't that big a deal in wheelguns but in carbines, it ends up blowing back into your face and THAT'S a little bit distracting.
I also suggest you get a either a bulky powder like Trail Boss or a powder that has a rather large powder charge. I've loaded .45 Colt with fast burning powders like Bullseye and those itty bitty 5 and 6 gr powder charges make it REALLY easy to double or triple charge a case if you aren't absolutely focused and paying close attention. It only takes one mistake like that to get your nickname changed to 'Stumpy'.
Another big thing about reloading .45 Colt is the crimp. You want a firm roll crimp. Heavier the crimp, the longer the brass has to fully expand in the chamber.
Lastly, I very strongly urge that you GET A RELOADING MANUAL or 2 (or 10-the more the merrier). For the money, Lyman's Cast Bullet Manual is the best bang for the buck and I'd suggest either Speer or one of the powder manufacturers as a secondary source as well. There's always some new information you can find in the different manuals and I always cross reference between at least 2 of them when I'm doing load development. That way, I can double check for typos (and I've found some in every manual I own) before I start pouring powder.