I have done some personal testing of the Glaser Safety, and the Mag-safe ammo in .45ACP,.38 special, .380 and .25ACP. To sum it all up they penetrate deeper than anything else that I tried (both ball and JHP) and they make a big cavity at the termination point of the channel. All of the rounds were very accurate at 25 yrds. especially the .25 ACP I could cover the group with my hand. Glaser says that glass defeats them and they recommend a double tap under those circumstances. Wood like 2x4's and hard oak planks do not stop them. They penetrate better than ball and make a big hole on exit. I have shot them into heavy polyethylene barrels 35 gal types the entrance hole is clean and the opposite side is full of a lot of little exit holes about two hand widths. The Mag-Safe are all I carry in the .25ACP and the .380. I carry JHP in all the other guns. I really like the Speer Gold dot JHP and JHP +P short barrel ammo for defense carry they function well are very accurate and penetrate deeply an excellent cartridge. Just my two cents from personal experience. I won't carry ammo that I haven't tested and I won't carry a gun that I haven't put 1000 rounds through under real world circumstances with reasonable accuracy.