jumeda33,
I have a number of High Noon Holsters. Most are Cowhide. As my body shape doesn't really lend itself to IWB, I own several versions of the Slide Guard for different pistols as they are OWB (I never tuck my shirt). I do own a Public Secret in Horsehide which is IWB. Most all of my Holsters are 15 degree cant, because as stated before...it hides the gun butt better. The Public Secret however is a O-zero cant.
All statements regarding Horsehide being the tighter grain and therefore more resistant to moisture is right on the money, and is therefore a tad more money to purchase. My experience with High Noon Holsters has been great. I hate the waiting 12 weeks or so to get their holsters, but they are worth it when you get them. However, do check out the in stock holsters as sometimes you can find something there and not have to wait.