Thanks all, for your insight. In my situation it's a matter of what I can carry on an every day basis at work, where I have to be extremely careful of concealment. On the weekends I carry an FEG P9R, but that's too bulky for the office. I have a Makarov in .380 that is easier to conceal, but too heavy for pocket carry. So, not wanting to have to purchase too many different calibers of ammo, I'm only looking at 9MM and .380.
I do prefer the stopping power of a larger round (I would love to carry a .45 at all times) but merging affordability, reliability, concealment and stopping power in a pair of dress pants gets to be difficult!
I appreciate your wisdom.